Tom Bossert - Cybersecurity Executive Order Briefing free essay sample

The Meaning of a Work of Art, Media or Design Is Not Fixed, Whatever the Intetions of the Maker Essay Example

The Meaning of a Work of Art, Media or Design Is Not Fixed, Whatever the Intetions of the Maker Essay Example The Meaning of a Work of Art, Media or Design Is Not Fixed, Whatever the Intetions of the Maker Essay The Meaning of a Work of Art, Media or Design Is Not Fixed, Whatever the Intetions of the Maker Essay The meaning of a work of art, media or design is not fixed, whatever the intetions of the maker. Choose a specific example and discuss: How it’s meaning might change depending on where it is seen and by whom. Introduction; The meaning of a work of art, media or design may or may not change depending on the audience viewing the object. The object will not change in appearance, but will the perception? Throughout this essay I will explore whether the meaning could actually change depending on who it is seen by and where it is seen. I will do this by discussing the intent of the directors, photographers and artists to gain full information of why the creator first intended to create and did it fulfill the reason. Also I will research some of the world’s most famous well known mediums and what makes them an important part of todays society and can we as the public really commit to liking them because they are our personal taste and opinion or do we enjoy them because of the background and intent of the creator, or maybe just because they are famous. a photograph should clearly show the intention of the photographer† -Martin Parr 1952 (bibliography) I found this quote by Martin Parr it particularly interested me because of the way it shows that not all photographers intent is the same. Parr has many quotes in his books and from articles I have read (bibliography- books) They explain his theories of what the context of pictures should be. And argues why they should be like that†¦Ã¢â‚¬ ¦(example of quote of argument bibliography) Martin Parr’s work presents the viewers and the audience with images that represent the place and the atmosphere with in them, the pictures maybe basic but beautifully captured, the intent of the pictures are not hidden nor do you have to look in depth for any meaning (bibliography of photo’s). This may be a good attribute about his work or a negative one, depending on the viewer. In one of Martin Parrs books alled ‘Our True Intent Is All For Your Delight: The John Hinde Butlins Photographs. ’ Parr’s opinions of other peoples work became clear when he was interviewed for the book about John Hinde in the 90’s. After parr who worked along John Hinde and then became a fan, collecting his work since 1971. â€Å"British postcard photographer John Hindes glowing color images of Butlins Holiday Camps in the 60s and 70s, presented and with an introduction by Martin Parr† (bibliography- suite101. om/content/our-true-intent-is-all-for-your-delight-a84653) The introduction said that â€Å"As with all Hinde imagery, they show an idealised view of the world and, after the passage of time, acquire the power of a lost dream. The most remarkable thing of all is that the cards were painstakingly produced not for any aspirational ideas or as great art, but as humble postcards to sell for a few pence to holidaymakers. † This particular introduction by Martin Parr really gave me an idea of what the British photographer liked as a person and what work he really admired to see and what influenced him. To me their work are rather similar and inspired Parr to publish one of his most recent books ‘Boring Postcards’ 1999 and 2000; the Boring postcards of the 1960’s-1970’s include a selection of Hides work. thingsmagazine. net/text/t15/postcards. htm This blog by jonathon bell- ‘what goes around, comes around’ gives the reader the idea of an unbiased and open opinion of the book and what he think’s the book it about. I found that reading the blog made me feel that is the intent of the photographers work really the main objective here? nd is it all just contradiction. For example Martin Parr deliberately puts forth in interviews and in his literature that the intent should be clear in the photograph and should be hidden (QUOTE by martin parr). Through reading the passage by Jonathon Bell going into depth about what the picture meant to him, and what the photograph portrait made me think did Martin Parr mean for this to happen â€Å"Are th ese visual portents of trouble ahead the key attraction? For those of us unfamiliar with the dark art of the stylist or the existence of light pimps and backstreet Seventies stereo specialists, Boring Postcards is streaked through with regret. Here is a world that might have been. It’s hard to tell when the scales fell from our eyes and modernism – in all its variants – began its long spell in the wilderness† Martin Parr’s ideological way of taking photographs can be compared with many contemporary

What is a Hero Essay Example | Topics and Well Written Essays - 500 words

What is a Hero - Essay Example They are tempted to use their great strength to do good for themselves or their cause, but they have limitations that they may not know. In this way the heroes of epic stories tell us something about ourselves: although human beings are the strongest species on the planet we can often harm ourselves through our hubris. Hubris and Nemesis are issues that all heroes must face often on a huge and dramatic scale. In the end however, a hero is someone who proves their mettle by putting others interests before their own. A good example is in The Odyssey a remarkable story of one man’s journey back home, a journey of return to his loved ones. For Odysseus, nothing is more important that family. That said, there are other values in the story that are very important. One is a collection of martial values—honour, fellowship, solidarity—that runs like a golden thread throughout the story. Another is the duty of the living towards the dead. All of these have played an important role in my own life. Just as Odysseus tries to live his life according to this values—familial love, martial honour, and duty to those gone before us—so do I try to live my own life. It is the story of a man trying desperately to return home after many years away fighting in a terrible war. But he is being punished and his journey is very dilatory. He must constantly deal with obstacles. Each obstacle presents in its way a moral or ethical challenge that will try Odysseus. Although my own life is very different that Odysseus’, and much less straightforward, nevertheless, I too have been challenged by obstacles that have made me think hard about the values I live by. Throughout the story he does everything possible to put the interests of his crew and family before his own. He shows that at the core of all true heroes is love. Also, his associations make him heroic. He surrounds himself with

Reading Guide #2, for Augustines Confessions, Bks 7.5 8 Essay

Reading Guide #2, for Augustines Confessions, Bks 7.5 8 - Essay Example A human has to understand what is bad to see what is good. It is impossible to judge without knowing and experiencing. Therefore, God lets people face evil to make them understand what good really is and how valuable it is. People appreciate good after being exposed to evil. Otherwise, they would simply fail to know what good means and why good is essential for them. It is a trivial metaphor but it is very precise: there is no light without shadow and there can be no good without evil. Hence, I do not agree with Augustine that evil does not exist as evil is a part of the multifaceted world. Augustine is strongly opposing sex as he sees it as â€Å"the vileness and the shame† (Augustine Bk 8, Ch. 11, par. 26). The thinker sees attraction to sex as certain kind of return to the life without God, i.e. life without knowledge and enlightenment. He sees people as creatures who focus on their desires that have nothing to do with their souls or a better world. This viewpoint is similar to Cyprian’s views on sex. Both saints stress that people have to be virtuous especially those who devote their lives to God. I agree that the priest and those who devote themselves to God have to keep to celibate. However, people living in the secular world do not need to keep to such strict rules. Otherwise, the humanity will simply cease to exist. At the same time, there should be certain purity and men as well as women have to understand that sex is only a part of their lives given by God. It is not a human’s primary concern. People have to focus on self-development thou gh sex should not become something banned or stigmatic. Clearly, every individual desires to have a good family, a decent job, and loyal friends. It is not a shameful desire. However, this is not the finite goal as this is only certain premise for further development. A man can have favorable conditions to live in and strive for self-development. Self-development and impact on the world are two

Managing Change in the Urology Department of a National Health Service Essay

Managing Change in the Urology Department of a National Health Service Hospital in England - Essay Example It is clear from the discussion that the events that caused the need for change in the hospital were the combined financial crisis and the newly introduced regulations on the number of working hours for hospital personnel. Improving the situation will require the application of effective strategies and techniques that would change the current situation. The strategies and techniques require efficient processes and procedures. The hospital should be prepared to apply efficient change initiatives that are inclusive and address the needs of all the stakeholders. Otherwise, resistance will arise among the stakeholders. The three crucial areas that require the change include stakeholder/employee relationships, management of technological change, and worker motivation. This report begins with the summary of the organization that paves way for discussion on the issues that require close attention. The mission of the National Health Service Hospital in England is to sustain continuous improv ement in the delivery of health care services. The management seeks to ensure a healthy working environment for the employees as well as other stakeholders. The Department of Urology is struggling to respond to external pressures for change that have threatened its ability to offer efficient medical care. The hospital works with five consultant surgeons, a few middle-grade and junior doctors, a range of nurses and other clinical personnel. The hospital infrastructure is not efficient enough to offer competitive and efficient health care services. The events that triggered a need for change in the hospital were the combined financial crisis and the newly introduced regulations on the number of working hours for the hospital personnel. The introduced regulations on treatment duration made the hospital sub-contract some of the treatments to a private hospital, leading to financial losses. The factor that contributed to the shortage of medical staff is the conflict in the regulations in volving the working hours. The management of the crisis is loaded with many challenges such as the tension between managers and clinicians and failure to agree on the staff capacity, allocation of extra beds, and operating theater. Others include information overload, ineffective problem solving, disagreement on the number and qualifications of new entrants, and inefficient data collection. The current challenges facing the Urology Department of the National Health Service Hospital in England are related to the incompetence of the stakeholders in managing the changes facing the health care industry. Change Management Change management is a structured process designed to deal intentionally and directly with human

advantages and disadvantages of vaccinations

advantages and disadvantages of vaccinations Introduction Vaccination or immunization is a means of providing specific protection against many common and damaging pathogens by stimulating an organisms immune system to either produce humoral antibodies against the pathogen (or toxins produced by the pathogen) or T cells that can provide cell-mediated immunity (Ghaffar and Haqqi, 2010). Though ancient scientists did mention about prevention of infectious diseases through immunisation, it was Edward Jenner who developed the first vaccine. The vaccine was developed against small pox in the year 1796. The next vaccine came up almost a century later by Louis Pasteur. The vaccine was anti-rabies vaccine and was first used in 1885. The development of anti-rabies vaccine kindled hope for prevention of other infectious diseases, leading to immense research and development of several other vaccines (Shah, Nitin and Kukrej, 2007). The term vaccination was coined by Edward Jenner. Vaccination is the method of causing immunity to a disease by administration of an antigenic material into the body. The term vaccination is used interchangeably with immunity, which is derived from the Greek word immune which means to be protected. Several vaccines have been developed which either prevent or ameliorate several infectious diseases. The first disease for which vaccine was developed is small pox. Infact, even before Edward Jenner developed a proper vaccine against small pox, people in India and China inoculated fluids taken from small pox vesicles of patients suffering from mild course of disease. Despite the marked usefulness of vaccination in the prevention of infectious diseases, vaccination is still a much debated topic and has several medical safety, ethical, political and religious implications. In this essay, vaccination, types of vaccines, implications of vaccination and novel vaccines will be discussed with reference to recent literature. Mechanism of action of vaccines Vaccines act by developing immunity to the particular disease by inducing the development of antibodies. There are basically 2 types of immunity, innate immunity and acquired immunity. Innate immunity develops after actual exposure to the disease organism. Acquired immunity develops after exposure to vaccination. Acquired immunity may be active or passive immunity. Active immunity is that immunity that develops following exposure to antigenic stimulus, while passive immunity develops after direct injection of antibodies in the form of either sera or immunoglobulins, inside the body. The type of immunity rendered by vaccination is active immunity. Passive immunity confers temporary protection. The antibodies are taken from individuals or animals who are already infected with the disease. Active immunity renders long term protection (Ghaffar and Haqqi, 2010). A pathogenic infectious agent induces disease and at the same time triggers the immune system of the host to develop antibodies against the disease. These antibodies help in the recovery of the host from the disease and continue to offer protection to subsequent infections from the same pathogen. This principle has been used for vaccination. Through vaccination, antigens which mimic the original pathogen of the respective disease are introduced into the body. The antigens only trigger the immune response, but do not cause the disease. The immune response may be cell-mediated or humoral, or even both, depending on which series of T helper lymphocytes are stimulated. Stimulation of Th1 series leads to lymphocytic response, while stimulation of Th2 series leads to humoral response. The timing of vaccine is based on several factors, the most important of which is the susceptibility of the disease, reactogenecity and presence of maternal antibodies. Thus, BCG and OPV vaccines are given at birth, because the child can get exposed to tuberculosis and polio at birth due to absence of maternal immunity and risk of susceptibility at this age. Similarly, vaccines against diphtheria, tetanus, pertussis, hemophilus influenza are given in early childhood for maximum reactogenecity and protection against the diseases (Shah, 2007). Many vaccines are given together and this makes sense because concurrent administration of more than one vaccine does not interfere with the take of one another. It is important to give atleast 4 weeks time before the administration of second dose of the same vaccine (Shah, 2007). Types of vaccines The antigens in vaccines may be either live organisms, modified exotoxins, subunits of organisms or whole inactivated organisms. There are basically two types of vaccine: live vaccines and inactivated vaccines. In live vaccines, the pathogen, either virus or bacteria is weakened or attenuated. They act by causing non-clinical and self-limiting disease, thus triggering the immune system and inducing immunity. On administration, the pathogens multiply in the host and trigger immune response. The pathogens do not cause any disease because they are attenuated. However, in immunocompromised patients, live vaccines can cause disease. One major advantage with live vaccines is that a single dose is sufficient to confer long-term immunity. Examples of live vaccines are oral polio vaccine, measles vaccine, mumps vaccine and yellow fever vaccine (Ghaffar and Haqqi, 2010). Inactivated vaccines consist of either killed pathogens, subunits of pathogens or toxins released by pathogens. The killed vaccines are made up of pathogens which are grown in suitable culture, subsequent to which the pathogens, either bacteria or virus are killed either thermally or chemically with formaldehyde. More often than not, the polysaccharide immunogenic antigen is binded chemically with a protein molecule, to enhance the immunogenecity of the vaccine. Inactivated vaccines have to be given in multiple doses. The immunity is for a short period. Hence boosters doses are essential. Examples of inactivated virus vaccines are, hepatitis A vaccine, inactivated polio vaccine and rabies vaccine. Inactivated bacterial vaccines are whole cell killed typhoid vaccine and pertussis vaccine. Viral subunit vaccine is HBsAg vaccine. Toxoid vaccines are tetanus and diphtheria vaccines. Capsular polysaccharide vaccines are hemophilus influenza, typhoid Vi, pneumococcal and meningococcal vacc ines. In these vaccines, though the pathogens are destroyed and are not able to undergo replications, the capsid proteins, which are antigens are recognized by the immune system of the vaccinees, causing an immune response (Ghaffar and Haqqi, 2010). Bacterial subunit vaccine is acellular pertussis vaccine. Sub-unit vaccines are those which use purified components of the cell wall to initiate immune response in the vaccinee. Some of the examples of such vaccines are meningococcus, pertussis, hemophilus and pneumococcus vaccines. An interesting vaccine worth discussing at this juncture is the hepatitis-B vaccine which is developed by purification of the antigenic proteins that are manufactured subsequent to expression from a gene that is cloned into a vector like yeast (Ghaffar and Haqqi, 2010). Polysaccharide vaccines are basically weak antigens that are T-independent and hence cause IgM responses without development of immunologic memory that is critical for stable and long-term imm unity. In such vaccines, the immunogenecity is enhanced by conjugating the antigens with other proteins like meningococcus, hemophilus and pneumococcus that are T-dependent and induce immulogic memory (Ghaffar and Haqqi, 2010). The type of vaccination needed for a specific disease depends on the pathogenesis of the disease. For example, pathogens like diphtheria and tetanus cause the disease by releasing certain toxins called exotoxins. In these cases, antibodies which neutralise and prevent the binding of the exotoxin to respective receptors on the target cells prevent the disease. Thus vaccines against diphtheria and tetanus are toxoids. On the other hand, other pathogens have other pathogeneses, and consequently, antibodies which either react directly with the pathogen or eliminate the pathogen through either intracellular killing, complement mediated lysis or phagocytosis are essential. Pathogens like protozoa, viruses and intracellular bacteria which harbor inside the cells cannot be accessed by the antibodies and in such diseases, cells harboring the pathogens need to be destroyed (Ghaffar and Haqqi, 2010). Immunity conferred by a particular vaccine may be either lifelong or may last for few months. Examples of former type of vaccines are mumps, rubella, measles, tuberculosis, small pox and yellow fever. Cholera vaccine confers immunity only for few months and hence may be used only during outbreaks. Vaccines like diphtheria, tetanus, pertussis, polio and hemophilus influenza are part of primary immunization and must be given between 2-3 months of age. Mumps, measles and rubella vaccines must be given between 13- 15 months (Shah et al, 2007). Adjuvants Adjuvants are those chemicals which are added in the vaccine to enhance the immunogenecity of the vaccines. The most widely used adjuvants are aluminum salts, which are used in DPT. Other adjuvants which are in experimental stage include Freuds complete and incomplete adjuvants, certain oligonucleotides and some synthetic polymers. Certain bacteria also act as adjuvants and examples are Nocardia and BCG. Adjuvants increase immunogenecity by recognizing TOLL-like receptors, leading to activation of mononuclear phagocytes and induction of certain cytokines which enhance Th1 and Th2 responses (Ghaffar and Haqqi, 2010). Prophylactic and therapeutic immunisation Most of the vaccines are given as a prophylactic measures against their respective diseases, in the sense, the vaccines are given prior to exposure to the disease pathogen. In case of rabies and tetanus, the vaccination is given after exposure to the pathogen and this is known as post-exposure immunization. In some situations like tetanus, which has very short incubation period, both active and passive immunisation may be necessary post-exposure (Shah, 2007). Strains used Only particular strains are used for the development of any vaccine. Danish 1331 and Copenhagen are the commonly used strains in the BCG vaccine. Both are strains of mycobacterium bovis. In each 0.1ml, 0.1- 0.4 million live viable bacilli are present. Each vial of OPV vaccine contains more than one million inactivated viruses 1,2 and 3. Measles vaccine is derived from live attenuated Edmonston Zagreb strain that is grown in the human diploid cell culture. MMR vaccine vaccine contains 1000 TCID50 of measles, 5000 TCID50 of mumps and 1000 TCID50 of rubella virus . There are several strains from which measles vaccine is developed and they are Edmonston Zagreb, Schwarz, Moraten and Edmonston B strains. The strains are grown in human diploid cell culture and live attenuated viruses are used to prepare the vaccine. Of these, Edmonston Zagreb strain is the most commonly used strain. The mumps strains used are Urabe AM9, Leningrad-Zagreb, RIT 4385 or Jerryl Lynn. The efficacy between various strains is similar. The strains are grown in chick embryo or human diploid cell cultures. For preparing the rubella vaccine, the strain used is RA 27/3 vaccine strain. The virus is grown in human diploid or chick embryo cell cultures. Live attenuated form of the virus is used for preparation of the vaccine (Shah, 2007). Market availability BCG vaccines are available in multi-dose dark colored ampoules. Single dose vaccine is not available. The vials are available as 10-dose vial and 20 dose vial. The 10 dose vial has to be reconstituted with 0.5 ml of normal saline and the 20 dose vial has to be reconstituted with 1ml sodium chloride solution (Shah, 2007). Storage Storage again, depends on the type of vaccine. Constituents of BCG vaccine are freeze-dried and can be stored at temperatures between 2-80 degree centigrade for one year. The preparation is vacuum sealed. Hence the ampoule must be opened carefully after gradual filing to avoid sudden entry of air and spillage of the contents. Reconstitution is done using normal saline. The vaccine has no preservative and thus the chances of bacterial contamination are high. Hence after reconstitution, the vaccine must be used within 4 hours and the left over vaccine must be discarded. Until those 4 hours, the vaccine has to be stored between 2- 8 degree centigrade. Oral polio vaccine contains stabilising agent magnesium sulphate and hence is stable after refrigeration. At state and district levels, the polio vaccine stocks must be stored at -200 degree centigrade. In clinics, it must be stored in the freezer. While transferring the vaccine to an outreach facility, the vaccine must be carried in prope r vaccine carriers loaded with ice packs to maintain temperature between 2- 80 degree centigrade. DPT vaccine has to be stored between 2-8 degree centigrade. The vaccine should never be frozen and any vial accidentally frozen must be discarded. Measles vaccine can either be frozen or stored in refrigerator compartment (Shah, 2007). Shelf life Shelf life varies from vaccine to vaccine. While some vaccines can be stored for several years, some others can be stored only for few months. For BCG, when stored under recommended temperatures in dark place, the shelf life is 24 months. Measles vaccine is supplied as freeze-dried and the shelf-life is 1-2 years or even more (Shah, 2007). Reconstitution While some vaccines like DPT and typhoid are ready-to-use vaccines, others like BCG, measles and hemophilus influenza vaccines are freeze dried need to be reconstituted with appropriate solutions. BCG vaccine has to be reconstituted with sodium chloride solution provided by the manufacturers. measles vaccine must be reconstituted with sterile water. The vaccine does not have any preservative and hence strict asepsis must be maintained while diluting and aspirating contents. Reconstituted vaccine must not be stored (Shah, 2007). Administration Site and mode of administration depends on the vaccine. For BCG, the vaccine can be given anywhere. However, the recommended site is the convex aspect of the left shoulder for the purpose of easy visualization of the scar. The most preferred site of injection is the site at which the deltoid inserts into the humerus. Injection at sites higher than this level on the arm are likely to develop keloid (CDC, 2009). Oral polio vaccine is administered orally. The principle behind oral vaccination is that high gut immunity levels prevent transmission of the wild or pathogenic polio viruses. DPT, Hemophilus influenza, inactivated polio , hepatitis A, hepatitis B, typhoid, and other such vaccine shave to be given intramuscularly and measles, mumps, rubella and varicella vaccines need to be given subcutaneously. The seroconversion rates of the oral polio vaccine are variable. For polio viruses type- 1, 2 and 3, the seroconversion rates after one dose of vaccine are 73%, 90% and 70%. Hence multiple doses are recommended to achive seroconversion of 90- 95 percent for all the 3 types of vaccine (Shah, 2007). Advantages of vaccination The advantages of vaccines are innumerous and hence all countries in the world have adopted vaccination in their public health policy. infact, vaccination is the best means of prevention of certain infectious disease, especially in new borns, infants and childrens who are vulnerable to certain diseases. In many cases, even if the vaccinee develops the disease for which he or she is vaccinated, the course of the disease is usally mild and recovery is fast. Attenuated vaccines trigger all phases of immune system and confer more stable immunity. Most live attenuated vaccines need no boosters. they are cheap and immunity develops quickly. The drugs are easy to transport. Some live vaccines like oral polio vaccine are easy to administer, can be given orally (Shah, 2007). Vaccines are useful not only to prevent disease, but also to eradicate the disease from the globe. Small pox, a deadly poxy disease was eradicated from the world only through vaccination. Currently, polio is on the verge of eradication because of oral polio vaccines and inactivated polio vaccine. However, there is ongoing debate about the continuing use of these vaccines with respect to community protection, as against individual protection. This debate arises in the wake of rising cases of paralytic poliomyelitis and vaccine derived polioviruses with oral polio vaccine (Thacker and Shendurnikar, 2003). Researchers are under the opinion that once poliovirus is eradicated, vaccine derived poliomyelitis will surge if oral polio vaccine administration is continued. To gaurd the development of this problem, inactivated polio vaccine which is administered in the form of injection is being introduced even in developing and underdeveloped countries (Shah, 2007). Bacillus Calmette Guerin vaccine or BCG vaccine is a vaccine against tuberculosis that was first developed in 1921 by Albert Calmette, a French microbiologist and Camille Guerin, a veterinary surgeon. Currently, BCG is the only vaccine against tuberculosis. The mechanism of immunity induced by this vaccine is cell-mediated immunity. The protective effect of this vaccine is not very good, especially for pulmonary tuberculosis ( Vaccines are a of immense economic value in the health care system and this is evident from the cost-benefit ratios (1:10) of poliomyelitis and measles (Mason et al, 2002). However, in developing and underdeveloped countries many people do not have the access to many vaccines due to lack of infrastructure, coordinated health policies and cost factor. Disadvantages of vaccination Vaccination is associated with many side effects. However the benefits of vaccination outweigh the disadvantages of vaccination. The safety of vaccines is always a disputed aspect, expecially by critics. However, vaccines are selected basically based on the necessity, safety and efficacy and they licensed only after undergoing 3 phases of trials. The first phase is on human volunteers for safety and tolerance aspects. The second trial tests immune response and safety in human volunteers and the third trial checks for field efficacy nd safety. After these trials, potency, purity and sterility tests are performed by both the manufacturer and the Drug controller of the country and only when these are satisfactory is the vaccine released into market. The efficacy of certain vaccines like BCG is doubted. While many studies have shown this vaccine to be efficacious, promoting its ised in Asian and African countries, the vaccine is not recommended for routine use in the United States because of the doubts casted on the benefits of the vaccine through some studies (CDC, 2009). Improper manufacturing of inactivated vaccines can result in infections due to intact pathogens. Booster doses are essential for inactivated vaccines because the antigens cannot reproduce and thus periodic reinforcement of immune response is mandatory (Ghaffar and Haqqi, 2010). Some previous studies published a causal relationship betwen measles-mumps-rubella vaccine and autism. However, the Institute of Medicine nd Immunisation Safety Review Committee (2004) investigated the relationship and rejected the causal relationship. Though vaccination against varicella is highly efficacious, many experts do not recommend the vaccine because naturally acquired immunity offers protection life long and prevents adult chicken more which is more severe than childhood chicken pox. Infact, some studies have shown that iniversant infant vaccination of chicken pox will cause a surge in chicken pox in adulthoos and during pregnancy. Based on these studies, experts are of the opinion that though chicken pox vaccination prevents economic loss due to loss of work time, health care costs may arise (Ferson, 1995). Some experts are of the opinion that the shift of surge in cases towards adulthood and oldage can be minimised by administering the vaccine in 2-3 doses, instead of single dose (Senterre, 2004). In some countries, a new combination vaccine consisting of vaccines against measles, mumps, rubella and varicella has been developed. While the argument as to whether universal vaccination against varicella continues, this co mbination vaccine is viewed from a critical point because of increased risk of febrile seizures. (Klein et al, 2010). Vaccine against Japanese Encephalitis, a zoonotic viral disease is widely used in countries in Asia. The vaccine is an inactivated vaccine developed from infected brain tissue of mouse. This vaccine is expensive and needs to be administered in 2-3 doses. Even booster dose is required for this vaccine. However the vaccine is associated with adverse reactions in significant number of people. In China and other regions like Korea, a cheap vaccine is used with strain SA 14- 14- 2. This vaccine is not associted with significant allergic reactions. Though the vaccine has been deemed effective, there are not many trials to support the safe and efficient use of this vaccine (Plesner, 2003). Some vaccines are very costly. For example, the vaccines against HPV virus, for the prevention of cervical cancer are around 100US dollars. The efficacy of the vaccine is 70 percent and hence screening for cervical cancer needs to be done even despite vaccination. The vaccine has to be given in 3 doses and many people cannot afford the price (Madrid-Madrina, 2009). Live attenuated vaccines are difficult to transport and have a risk of undergoing secondary mutation which can cause virulence. Also, these vaccines can cause disease in immunosuppressed persons, which makes them useless in those with immunocompromise. It is for these reasons that live oral polio virus vaccine, also known as the Sabin vaccine is being gradually replaced by inactivated polio vaccine or Salk vaccine. Almost all vaccines have some adverse effects. The most common adverse effect is soreness and redness at the site of injection. other adverse effects include fever, malaise, disconfort, allergic reaction or even neurological problems. The type of side effect depends on the vaccine. In BCG, adverse reaction in the form of papule and ulcer formation is an indication of successful vaccine administration. Soon after the vaccine is administered a wheal of atleast 5 mm develops which is an indication that the vaccine was administered in the most appropriate manner. After about 2-3 weeks, a small papule develops at the site of injection which gradually increases in size to about 4- 8mm by the end of 5-6 weeks. After about 6 weeks, the papule ruptures and an ulcer develops. This ulcer heals slowly and develops a scar after 6- 12 weeks. Other undesirable adverse reactions can occur in 1-10 percent cases. They are delayed healing of ulcer, lymphangitis, enlargement of ipsilateral cervical and axillary lymph nodes, abscess formation, osteomyelitis and rarely disseminated BCG vaccination. After DPT administration, side effects in noted in more than 40 percent of vaccinees. The most common adverse effect noted is pain and redness at the site of injection. The pain may be so severe that the child may not be able to move the limb and walk. Induration and swelling may also be present. Fever is also very common. It may last for 24- 72 hours and responds well to paracetamol. All children who have been administered this vaccine must receive paracetamol whether there is fever or not, for control of pain. Other systemic side effects include vomiting, anorexia, irritability, lassitude and excessive crying.The side effects are due to pertussis vaccine. Rarely, seizures can occur after administration of the vaccine. For vaccines like measles and varicella, rash and fever many occur (Shah, 2007). Some adverse effects can be nasty. For example, Swine flu vaccine is associated with Guillian barre syndrome, anaphylactic shock, vasculitis, paralysis and even death and this aspect is preventing many individuals from taking the vaccine.(Menzies et al, 2008). Pneumococcal vaccine can rarely can anaphylactic shock or even convulsions (Haber et al, 2009). Thus vaccination is associated with several risks and prior to administration of vaccines, the risks and benefits must be ascertained. Combination vaccines 2 ore more vaccines can be either given together at the same time. Currently, two or more vaccines are administered through the same injection. The combination depends on the vaccine and the manufacturers criteria. For several years, diphtheria, tetanus and pertussis were given as combination vaccine, known as DPT. Similarly measles, mumps and rubella are also available as combination vaccines. other recent combination vaccines include hepatitis A and B vaccines, DPT with hemophilus influenza and inactivated polio vaccine, etc. Combination vaccines are safe and reduce the number of injections that need to be given to the child. They do not decrease the efficacy of vaccination. They increase the compliance to vaccination (Shah, 2007). Novel vaccines Some novel vaccines have been developed and are under trial in the wake of debate between advantages and disadvantages of current vaccines available. Some of the important ones are DNA vaccines, immunodominant peptides and anti-idiotype molecules. of recent interest in the field of vaccination are plant-vaccines, which are erived from plants and can be administered orally or through oral mucosa (WHO, 2010). The vaccines derived thus are expected to be cheap with minimal side effects. research in plant vaccines is a result of revolution in proteomics and genomics, and greater understanding of the molecular basis of infectious diseases and advances in modern biotechnology. Edible plant vaccines employ a new strategy of combining plant biology with medical science. Research has shown that some variants of tobacco express hepatitis B surface antigen and streptomutans surface protein and infact the torch of research in plant-derived vaccines is taken from here. Novel vaccines have only su b-units of the pathogen and hence do not cause any virulence even in immunosuppressed patients. other than tobacco, other plants which are potential sources of vaccines are tomato, banana, alfalfa, legumes and certain cereals (Refer figure and tables below). Some research has pointed to the role of oral transgenic plant-derived vaccines in the prevention of diarrhoeal diseases by some pathogens like norovirus, enterotoxigenic Escherichia coli and cholera (Tacket, 2004). Plant-derived vaccines have several advantages. Besides lower cost of vaccination, another major advantages of the vaccines are that they are administered orally and hence the need for injection equipment is not needed. This decreases the risks associated with injections like unsafe injection, poor sterilization, misuse and reuse. The vaccines will need less rigorous formulations for manufacture and supply unlike injections. Another major advantage of plant-derived vaccines is heat stability which avoids the maintena nce of expensive cold-chains, and allows easy portability of the vaccine. Since most of the plant-derived vaccines are effective mucosally, it is an advantage because most infections are acquired through mucosa and mucosal immunity prevents entry of the pathogens into the host. Plant-derived vaccines can be given as combination vaccines. Plant derived vaccines can be given even for diseases not covered under regular vaccination like sexually transmitted diseases, dengue hookworm and HIV. The development of plant-derived vaccines is yet in cocoon stage due to return of investment doubts, uncertain licentures, limited human trials and lack of expertise (Arzten, 2002). Fig.1. Plant derived vaccine development strategy (Das, 2009). Table 1. Antigens produced in transgenic plants (Das, 2009) Protein Plant Hepatitis B surface antigen Rabies virus glycoprotein Norwalk virus capsid protein E.coliheat-labile enterotoxin B subunit Cholera toxin B subunit Mouse glutamate decarboxylase VP1 protein of foot and mouth disease virus Insulin Glycoprotein swine-transmissible gastroenteritis cornavirus Tobacco Tomato Tobacco Potato Potato, tobacco Potato Arabidopsis Potato Arabidopsis Table-2. Transient production of antigens in plants after infection with plant viruses expressing a recombinant gene (Das, 2009) Protein  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Plant  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Carrier Influenza antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tobacco  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     TMV Murine zona pellucida antigen  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tobacco  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  TMV Rabies antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Spinach  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   AFMV HIV-1 antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  AFMV Mink enteritis virus antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Black eyed bean  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   CPMV Colon cancer antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tobacco  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   TMV Table-3 Antibodies and antibody fragments produced in transgenic plants (Das, 2009) Antibody  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Plant IgG (k)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Transition stage analog  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco IgM (ÃŽÂ »)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   NP(4-hydroxy-3-nitrophenyl)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  acetyl hapten Single domain (dAb)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Substance P  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tobacco Single chain Fv  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Phytochrome  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tobacco Single chain Fv  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Artichoke mottled virus  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  coat protein Fab; IgG (k)     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Human creatin kinase  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Arabidopsis IgG (k)  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Fungal cutinase  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco IgG (k) and SIgG/A  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   S. mutagens adhesin  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Tobacco hybrid Single chain Fv  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Abscisic acid  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco Single chain Fv  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Nematode antigen  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco Single chain Fv  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  ÃƒÅ½Ã‚ ²-glucuronidase  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Tobacco   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  ÃƒÅ½Ã‚ ²-1,4 endoglucanase  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Single chain  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Atrazin, Paraquat  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Tobacco antibody fragment  Ã‚  Ã‚   IgG  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Glycoprotein B of  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Soybean   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Herpes simplex virus  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Conclusion

A Womans Career Path Essays -- Gender Studies

The statistics prove that women are making tremendous strides in achieving careers in a variety of fields that were almost exclusively the domain of men. This much heralded progress, spurred by the feminist movement and the rejection of more traditional and oppressive gender roles, has defied thousands of years of sexual subjugation and has proven that women can succeed at any occupation just as well men. However, as married women with children have moved into the role of (in many cases dominant) wage earner, they have left behind a vacuum where the job of homemaker use to be. In American working class culture there are mounting opposition and obstacles to choosing the job of raising children and taking care of the family. This reversal of conditions, pushing women out of the role they were previously forced into, can also have ill consequences on society. The role of homemaker was naturally placed upon women early in human history, presumably due to the vulnerability of human biology. In other animals, pregnancy and child birth typically does not leave the mother in a state of compromised mobility as is the case in human pregnancy. Our primitive ancestors, sustaining themselves through hunting and gathering, would not likely have placed pregnant women in the role of as strenuous an activity as hunting. The role of rearing children and taking care of the home could then have justifiably been passed on to women. Arguably, the aggressive and dominant nature of the male gender, demonstrated even by modern apes for whom we share the closest biological link, would have been a force practiced by our ancestors to kept women in this role of subservience. In our society, where our biological makeup and physical abilities have very lit... ...age/> Gilbert, Susan. â€Å"Two Studies Link Child Care to Behavior Problems.† The New York Times Online. 16 Jul. 2003. Lu, et al. "Child day care risks of common infectious diseases revisited." Child: Care, Health & Development 30.4 (2004): 361-368. CINAHL with Full Text. EBSCO. Web. 17 Apr. 2011. Nelson, Sofia, and Lips, Hilary. â€Å"The Motherhood Penalty: ‘Sequencing Moms’ Pay a Price.† Women’s Media. 15 Dec. 2009 . Warren, Elizabeth. â€Å"Transcript. February 6, 2004.† Interview with Bill Moyers. NOW with Bill Moyers 06 Feb. 2004. Woolf, Virginia. The Death of the Moth and Other Essays â€Å"Professions for Women.† Harcourt Brace & Company, 1942 235-242

Collectivisation: Political Philosophy and Stable Income Essay

?How accurate is it to say that the most important result of the collectivisation of agriculture was that it imposed communist control of the countryside? The result of collectivisation of agriculture was that it had imposed communist control as it meant that all farmers got an equal and fair rate exchange from their produce. However some areas were capitalist such as the use of NEP, the idea that the more you work the more you gain and that peasants eventually gained land for their own increasing each individual profit which is not along the lines of communist views. It is accurate to a strong extent that collectivisation of agriculture was that it imposed communist control as Stalin removed capitalist ideas eventually such as the NEP, but by allowing farmers to own their own land meant that communist ideas had to be altered in order for Stalin to keep the support of the people. The political ideas of Stalin were by far to impose communist control. Stalin’s position meant that he could alter existing ideas in order to make them fit in with communist ones and therefore allowing him to take control of areas that before hadn’t followed communist ideas. This is seen when Stalin eliminated the NEP. By doing this he eliminated capitalist ideas as peasants were forced to hand over any land they owned and work on communal farms creating equality and communist control. The collectivisation of these farms meant that all farmers earned the same amount imposing communist control as there wasn’t certain members that earned more and so could cheat the government by selling on products in secret and earning more than others. However, over time more farmers began selling produce to kulaks that would make more money and therefore not following communist ideas. In order to stop this Stalin had to allow a small amount of land to be owned by each farmer, which meant that some capitalist ideas had to be used in order to keep farmers content. This shows how one of the most important results of collectivisation was that it imposed communist control but as people were not happy with this it meant some other ideas had to be brought in to allow a widespread acceptance. The ideology of Stalin was to communise peasants and therefore the government would have a stable income of grain to export and get income from. By collectivising peasants it meant that the government could control the production of grain by having a fixed amount of grain going to the government. This meant that the government could export this grain for a stable income. This had a positive effect for a short period of time before peasants wanted more of a share of grain and so the government had to allow this. This is also an economic advantage from collectivisation as the stable income allowed income for Russia that could go back into the country and therefore improve it. The collectivisation imposed communist control as without it the government wouldn’t have got such a stable income from exports that boosted the economy. Socially controlling the people by keeping them consent was very important. When peasants starting to act against the government by breaking machinery and killing off animals rather then hand them over to the government this mean that the government needed to take action. In order to solve this problem Stalin bought in a scheme that allowed each peasant to own a small piece of land in which they could work on and keep all the harvest from that land for themselves. This created a widespread acceptance for peasants and meant that people would accept Stalin’s policies and the communist control. This shows that the collectivisation had some problems that the government had to deal with that meant communist control wasn’t successful and so other capitalist ideas were needed to keep farmers happy. In conclusion, the most important result of collectivisation was that it imposed communist control as it meant that the government had control of the people socially, by allowing them to have their own land, and politically. It also meant that the government had a stable income from exports of grain allowing Russia to use that income to improve other areas. Without this control the government wouldn’t of been able to have the economic boost.

Woodrow Wilsons 14 Points Speech

Woodrow Wilsons 14 Points Speech On Jan. 8, 1918, President Woodrow Wilson stood in front of a joint session of Congress and gave a speech known as The Fourteen Points. At the time, the world was embroiled in the First World War and Wilson was hoping to find a way to not only end the war peacefully but to ensure it never would  happen again. A Policy of Self-Determination Today and then, Woodrow Wilson is viewed as both a highly intelligent president and a hopeless idealist. The Fourteen Points speech was in part based on Wilsons own diplomatic leanings, but also written with the research assistance of his secret panel of experts known as The Inquiry. These men included the likes of crusading journalist Walter Lippman and several distinguished historians, geographers, and political scientists. The Inquiry was led by presidential advisor Edward House and assembled in 1917 to help Wilson prepare to start negotiations to end World War I. Much of the intent of Wilsons Fourteen Points speech was to oversee the breakup of the Austro-Hungarian empire, set out the overarching rules of behavior, and ensure that the United States would only play a minor role in the reconstruction. Wilson considered self-determination a crucial part of the successful establishment of the disparate states in the aftermath of the war. At the same time, Wilson himself recognized the inherent danger in creating states whose populations were ethnically divided. Returning Alsace-Lorraine to France, and restoring Belgium were relatively straightforward. But what to do about Serbia, with a major percentage of the non-Serbian population? How could Poland have access to the sea without including territories owned by ethnic Germans? How can Czechoslovakia include three million ethnic Germans in Bohemia? The decisions that were made by Wilson and The Inquiry did not resolve those conflicts, although it is likely that Wilsons 14th point creating a League of Nations, was proffered in an attempt to build infrastructure to resolve those conflicts going forward. But the same dilemma exists unresolved today: How to safely balance self-determination and ethnic disparity? Summary of the Fourteen Points Since many of the countries involved in WWI had been drawn into it to honor long-standing, private alliances, Wilson asked that there be no more secret alliances (Point 1). And since the United States had specifically entered the war because of Germanys announcement of unlimited submarine warfare, Wilson advocated for the open use of the seas (Point 2). Wilson also proposed open trade between countries (Point 3) and the reduction of armaments (Point 4). Point 5 addressed the needs of colonial peoples and Points 6 through 13 discussed specific land claims per country. Point 14 was the most important on Woodrow Wilsons list; it advocated for an international organization to be established that would be responsible for helping to keep peace among the nations. This organization was later established and called the League of Nations. Reception Wilsons speech was well received in the United States, with some notable exceptions, including former president Theodore Roosevelt, who described it as both high-sounding and meaningless. The Fourteen Points were accepted by the Allied Powers, as well as by Germany and Austria as the basis for peace negotiations. The only covenant of the League of Nations that was totally rejected by the allies was a provision pledging the members of the league to ensure religious freedom. However, Wilson became physically ill at the start of the Paris Peace Conference, and French Prime Minister Georges Clemenceau was able to advance his own countrys demands beyond what was laid out in the 14 Points speech. The differences between the Fourteen Points and the resulting Treaty of Versailles raised great anger in Germany, leading to the rise of National Socialism, and ultimately the Second World War. The Full Text of Woodrow Wilsons 14 Points Speech Gentlemen of the Congress: Once more, as repeatedly before, the spokesmen of the Central Empires have indicated their desire to discuss the objects of the war and the possible basis of a general peace. Parleys have been in progress at Brest-Litovsk between Russsian representatives and representatives of the Central Powers to which the attention of all the belligerents have been invited for the purpose of ascertaining whether it may be possible to extend these parleys into a general conference with regard to terms of peace and settlement. The Russian representatives presented not only a perfectly definite statement of the principles upon which they would be willing to conclude peace but also an equally definite program of the concrete application of those principles. The representatives of the Central Powers, on their part, presented an outline of settlement which, if much less definite, seemed susceptible of liberal interpretation until their specific program of practical terms was added. That program proposed no concessions at all either to the sovereignty of Russia or to the preferences of the populations with whose fortunes it dealt, but meant, in a word, that the Central Empires were to keep every foot of territory their armed forces had occupied- every province, every city, every point of vantage- as a permanent addition to their territories and their power. Russian-Led Negotiations It is a reasonable conjecture that the general principles of settlement which they at first suggested originated with the more liberal statesmen of Germany and Austria, the men who have begun to feel the force of their own peoples thought and purpose, while the concrete terms of actual settlement came from the military leaders who have no thought but to keep what they have got. The negotiations have been broken off. The Russian representatives were sincere and in earnest. They cannot entertain such proposals of conquest and domination. The whole incident is full of significances. It is also full of perplexity. With whom are the Russian representatives dealing? For whom are the representatives of the Central Empires speaking? Are they speaking for the majorities of their respective parliaments or for the minority parties, that military and imperialistic minority which has so far dominated their whole policy and controlled the affairs of Turkey and of the Balkan states which have felt obliged to become their associates in this war? The Russian representatives have insisted, very justly, very wisely, and in the true spirit of modern democracy, that the conferences they have been holding with the Teutonic and Turkish statesmen should be held within open, not closed, doors, and all the world has been the audience, as was desired. To whom have we been listening, then? To those who speak the spirit and intention of the resolutions of the German Reichstag of the 9th of July last, the spirit and intention of the Liberal leaders and parties of Germany, or to those who resist and defy that spirit and intention and insist upon conquest and subjugation? Or are we listening, in fact, to both, unreconciled and in open and hopeless contradiction? These are very serious and pregnant questions. Upon the answer to them depends the peace of the world. The Challenge of Brest-Litovsk But, whatever the results of the parleys at Brest-Litovsk, whatever the confusions of counsel and of purpose in the utterances of the spokesmen of the Central Empires, they have again attempted to acquaint the world with their objects in the war and have again challenged their adversaries to say what their objects are and what sort of settlement they would deem just and satisfactory. There is no good reason why that challenge should not be responded to and responded to with the utmost candor. We did not wait for it. Not once, but again and again, we have laid our whole thought and purpose before the world, not in general terms only, but each time with sufficient definition to make it clear what sort of definite terms of settlement must necessarily spring out of them. Within the last week, Mr. Lloyd George has spoken with admirable candor and in admirable spirit for the people and Government of Great Britain. There is no confusion of counsel among the adversaries of the Central Powers, no uncertainty of principle, no vagueness of detail. The only secrecy of counsel, the only lack of fearless frankness, the only failure to make a definite statement of the objects of the war, lies with Germany and her allies. The issues of life and death hang upon these definitions. No statesman who has the least conception of his responsibility ought for a moment to permit himself to continue this tragical and appalling outpouring of blood and treasure unless he is sure beyond a peradventure that the objects of the vital sacrifice are part and parcel of the very life of Society and that the people for whom he speaks think them right and imperative as he does. Defining Principles of Self-Determination There is, moreover, a voice calling for these definitions of principle and of purpose which is, it seems to me, more thrilling and more compelling than any of the many moving voices with which the troubled air of the world is filled. It is the voice of the Russian people. They are prostrate and all but hopeless, it would seem, before the grim power of Germany, which has hitherto known no relenting and no pity. Their power, apparently, is shattered. And yet their soul is not subservient. They will not yield either in principle or in action. Their conception of what is right, of what is humane and honorable for them to accept, has been stated with a frankness, a largeness of view, a generosity of spirit, and a universal human sympathy which must challenge the admiration of every friend of mankind; and they have refused to compound their ideals or desert others that they themselves may be safe. They call to us to say what it is that we desire, in what, if in anything, our purpose and our spirit differ from theirs; and I believe that the people of the United States would wish me to respond, with utter simplicity and frankness. Whether their present leaders, believe it or not, it is our heartfelt desire and hopes that some way may be opened whereby we may be privileged to assist the people of Russia to attain their utmost hope of liberty and ordered peace. The Processes of Peace It will be our wish and purpose that the processes of peace, when they are begun, shall be absolutely open and that they shall involve and permit henceforth no secret understandings of any kind. The day of conquest and aggrandizement is gone by; so is also the day of secret covenants entered into in the interest of particular governments and likely at some unlooked-for moment to upset the peace of the world. It is this happy fact, now clear to the view of every public man whose thoughts do not still linger in an age that is dead and gone, which makes it possible for every nation whose purposes are consistent with justice and the peace of the world to avow nor or at any other time the objects it has in view. We entered this war because violations of right had occurred which touched us to the quick and made the life of our own people impossible unless they were corrected and the world secure once for all against their recurrence. What we demand in this war, therefore, is nothing peculiar to ourselves. It is that the world be made fit and safe to live in; and particularly that it be made safe for every peace-loving nation which, like our own, wishes to live its own life, determine its own institutions, be assured of justice and fair dealing by the other peoples of the world as against force and selfish aggression. All the peoples of the world are in effect partners in this interest, and for our own part, we see very clearly that unless justice be done to others it will not be done to us. The program of the worlds peace, therefore, is our program; and that program, the only possible program, as we see it, is this: The Fourteen Points I. Open covenants of peace, openly arrived at, after which there shall be no private international understandings of any kind but diplomacy shall proceed always frankly and in the public view. II. Absolute freedom of navigation upon the seas, outside territorial waters, alike in peace and in war, except as the seas may be closed in whole or in part by international action for the enforcement of international covenants. III. The removal, so far as possible, of all economic barriers and the establishment of an equality of trade conditions among all the nations consenting to the peace and associating themselves for its maintenance. IV. Adequate guarantees given and taken that national armaments will be reduced to the lowest point consistent with domestic safety. V. A free, open-minded, and absolutely impartial adjustment of all colonial claims, based upon a strict observance of the principle that in determining all such questions of sovereignty the interests of the populations concerned must have equal weight with the equitable claims of the government whose title is to be determined. VI. The evacuation of all Russian territory and such a settlement of all questions affecting Russia as will secure the best and freest cooperation of the other nations of the world in obtaining for her an unhampered and unembarrassed opportunity for the independent determination of her own political development and national policy and assure her of a sincere welcome into the society of free nations under institutions of her own choosing; and, more than a welcome, assistance also of every kind that she may need and may herself desire. The treatment accorded Russia by her sister nations in the months to come will be the acid test of their good will, of their comprehension of her needs as distinguished from their own interests, and of their intelligent and unselfish sympathy. VII. Belgium, the whole world will agree, must be evacuated and restored, without any attempt to limit the sovereignty which she enjoys in common with all other free nations. No other single act will serve as this will serve to restore confidence among the nations in the laws which they have themselves set and determined for the government of their relations with one another. Without this healing act, the whole structure and validity of international law is forever impaired. VIII. All French territory should be freed and the invaded portions restored, and the wrong done to France by Prussia in 1871 in the matter of Alsace-Lorraine, which has unsettled the peace of the world for nearly fifty years, should be righted, in order that peace may once more be made secure in the interest of all. IX. A readjustment of the frontiers of Italy should be effected along clearly recognizable lines of nationality. X. The peoples of Austria-Hungary, whose place among the nations we wish to see safeguarded and assured, should be accorded the freest opportunity to autonomous development. XI. Rumania, Serbia, and Montenegro should be evacuated; occupied territories restored; Serbia accorded free and secure access to the sea; and the relations of the several Balkan states to one another determined by friendly counsel along historically established lines of allegiance and nationality; and international guarantees of the political and economic independence and territorial integrity of the several Balkan states should be entered into. XII. The Turkish portion of the present Ottoman Empire should be assured a secure sovereignty, but the other nationalities which are now under Turkish rule should be assured an undoubted security of life and an absolutely unmolested opportunity of autonomous development, and the Dardanelles should be permanently opened as a free passage to the ships and commerce of all nations under international guarantees. XIII. An independent Polish state should be erected which should include the territories inhabited by indisputably Polish populations, which should be assured a free and secure access to the sea, and whose political and economic independence and territorial integrity should be guaranteed by international covenant. XIV. A general association of nations must be formed under specific covenants for the purpose of affording mutual guarantees of political independence and territorial integrity to great and small states alike. Righting Wrongs In regard to these essential rectifications of wrong and assertions of right, we feel ourselves to be intimate partners of all the governments and peoples associated together against the Imperialists. We cannot be separated in interest or divided in purpose. We stand together until the end. For such arrangements and covenants, we are willing to fight and to continue to fight until they are achieved; but only because we wish the right to prevail and desire a just and stable peace such as can be secured only by removing the chief provocations to war, which this program does remove. We have no jealousy of German greatness, and there is nothing in this program that impairs it. We grudge her no achievement or distinction of learning or of pacific enterprise such as have made her record very bright and very enviable. We do not wish to injure her or to block in any way her legitimate influence or power. We do not wish to fight her either with arms or with hostile arrangements of trade if sh e is willing to associate herself with us and the other peace-loving nations of the world in covenants of justice and law and fair dealing. We wish her only to accept a place of equality among the peoples of the world,- the new world in which we now live,- instead of a place of mastery. Neither do we presume to suggest to her any alteration or modification of her institutions. But it is necessary, we must frankly say, and necessary as a preliminary to any intelligent dealings with her on our part, that we should know whom her spokesmen speak for when they speak to us, whether for the Reichstag majority or for the military party and the men whose creed is imperial domination. Justice to All People and Nationalities We have spoken now, surely, in terms too concrete to admit of any further doubt or question. An evident principle runs through the whole program I have outlined. It is the principle of justice to all peoples and nationalities, and their right to live on equal terms of liberty and safety with one another, whether they be strong or weak. Unless this principle be made its foundation no part of the structure of international justice can stand. The people of the United States could act upon no other principle; and to the vindication of this principle, they are ready to devote their lives, their honor, and everything they possess. The moral climax of this the culminating and final war for human liberty has come, and they are ready to put their own strength, their own highest purpose, their own integrity and devotion to the test. Sources: Chace, James. The Wilsonian Moment? The Wilson Quarterly (1976-) 25.4 (2001): 34-41. Print. Jacobson, Harold K. Structuring the Global System: American Contributions to International Organization. The Annals of the American Academy of Political and Social Science 428 (1976): 77-90. Print. Lynch, Allen. Woodrow Wilson and the Principle of National Self-Determination: A Reconsideration. Review of International Studies 28.2 (2002): 419-36. Print. Tucker, Robert W. Woodrow Wilsons New Diplomacy. World Policy Journal 21.2 (2004): 92-107. Print.

Minsa essays

Minsa essays SOURCE: The Urian Anthology 1970-1979 REVIEW: Minsay Isang Gamu-Gamo Nicanor G. Tiongson, The Philippines Daily Express, 1976 Minsa'y Isang Gamu-Gamo: Filipino with a Passion Contemporary Filipino moviemakers who seek to paint authentic Filipino experience on screen have to steer a difficult course between todays Scylla and Charybdis. On the other hand, they must fight the currents of commercial formula films that can suck and drown them into a whirlpool of song-and-dance, and blood-and-thunder and tawa-iyak inanities. On the other hand, they must not run aground on the artistic rocks of Europeanized sensibilities that can crush and powder them into self-indulgent insignificance. Only a preciously few films have steered through this difficult course with some measure of success. Some, like Lunes, Martes... have come so perilously close to commercialism. Others, like Nunal, have all but been devoured by Frechified artistry and sensibility. A few, like Bitayin si Baby Ama, Sakada, Tatlong Taong Walang Diyos and Tiket Mama, Tiket Ale have come through with commendable colors. Filipinos should, therefore, rejoice that this year has witnessed the rise of a number of producers, directors and scriptwriters who have bravely defied the pull of commercialism and produced films that honestly and seriously attempt to limn the Filipino and his myriad experiences on screen. Minsay Isang Gamu-Gamo preeminently belongs to this gallery of authentic Filipino portraits. First and foremost credit must go to playwright Marina Feleo-Gonzales for creating a story and screenplay that is so passionately real and unequivocally Filipino. Using material from contemporary Philippine experience, Gonzales story successfully strips the mask off the so-called special relations between the Philippines an...

Financial Analysis of the Company Diageo Essay Example | Topics and Well Written Essays - 2250 words

Financial Analysis of the Company Diageo - Essay Example This essay stresses that Diageo is a leading firm which is spread globally and conducts premium drinks business with a varied collection of outstanding labels. Diageo is mainly concentrated in business regarding beverages. The firm, based in UK, manufactures its products in different countries of the world like Britain, Ireland, United States, Canada, Spain, Italy, Africa, Latin America, Australia, India, and the Caribbean. Based on research, it is seen that they sell their products approximately in 180 markets throughout the world. Diageo is an established firm and, thus, has its own authority in the production and sale of wine. Diageo manages 17 out of 100 of the top world’s spirit brands. The firm emphasizes its prime focus on developing its international brands in order to capture a giant market share. Diageo is listed in the London Stock Exchange (DGE) and for its American depositary receipts it is also listed on the New York Stock Exchange (DEO). This paper makes a conclusion that sales, accounts receivable and number of days outstanding or the turnover ratio provides a more or less indication of the firm’s current and future prospects. Economic recession has negatively impacted on the customer’s confidence and, thus, this has brought about a little negative diversion in business and its profits. â€Å"Diageo strength has driven competitive advantage in premiumisation†. Diageo faces competition from small and artisan wineries which also pose a greater threat to its market. An increasing competition from other drinks outside the wine industry is another threat for Diageo. Analysis of the Key Personnel within the Company: Diageo has more than 20000 talented people working with the firm. Diageo has a diverse workforce which corresponds to its widespread network throughout the globe. The staff of Diageo is committed in serving their customers, as customer satisfaction is the highest priority for Diego. The pr ime motto among employees is ‘

Mass Extinction Essay Example | Topics and Well Written Essays - 1250 words

Mass Extinction - Essay Example A life seen through the eyes of a forever-existing mountain, which has witnessed wonders and ruins forming the current space we are living in today. As a part of this holistic ecosystem, it is our responsibility to respond to the nature’s call. This paper sheds some light on this mass extinction by focusing on its causes to determine the effects brought about by this extinction to find out how man should respond to this phenomenon, and why it is important for man to act quickly. Sea turtles are inhabitants of all worlds’ oceans except for the arctic, and are referred to as marine reptiles. However, they have been listed as endangered, for their reproduction rate is so slow to cover up for its rapid decrease from the ecosystem due to man’s activities that threaten their survival. It is noteworthy that sea turtles play a significant responsibility to two ecosystems that are very important to the turtle’s themselves and to humans too. This is because in the s eas they eat the sea grass that grows on the sea floor. This is very important, for they function to keep them short enough to avail breeding and development locations for many fish species as well as other marine life (Elewa, 34). The sea turtle’s meat, shell and eggs ate so precious and forms one of the main reason as to why man continue hunting them at an alarming rate. This has greatly reduced its numbers as St Catherine’s Sea Turtle Conservation program reports that the nesting levels of sea turtles today are less than one percent of those in 1947 (Leakey and Lewin, 46). This is an immense decline that calls for mans attention to reclaim these turtles. Therefore, to prevent the loss of these creature, fishing nets should be designed a way to allow for escape of turtles because if trapped in the net they are bound to drown. This is because they naturally come to the surface of water to breath, and if trapped, they don’t get the opportunity to do this. Beach development should also be monitored so that they do not encroach more into the water bodies. This is because hatchlings are mostly affected b y light especially during the night. As talked about above, the mass extinction of sea turtles is majorly brought about by man and his activities. It is evident that these moral violations of man as well as their practices are set to drive the sea turtles into extinction. It is important for the public to be warned that this is an impending disaster if nothing is going to be done now. The debate as to whether man is capable of slowing the extinction seems to drag on as some opponents claim that it is too late for man to intervene. This happening as little by little man continues to take down the homes of millions of animal species for cultivation, settlement and other infrastructure, and this has doubled since 1960 (Goodale and Black, 22 ). Therefore, this indicates that more habitats will continue to be reclaimed by man as he continues to sa tisfy himself at the expense of other animals. The current extinction rate in the world over stands at ten thousand times faster than earlier recorded, and the highest for that matter (Garner, 23). Is this the sixth extinction? Scientists are of the opinion that these reductions in biodiversity have already stated having an impact on human life. With the belief that the world is in the middle of a mass extinction, it implies that the millions of people who are indeed contributing to this extinction of animals will face food